The volume of blood ejected into the aorta during the systole generates a wave (pulse wave), circulating through the arterial system with a certain velocity (pulse wave velocity, PWV). Pulse wave velocity can be measured non-invasively and is used to estimate arterial stiffness.
How are stiff arteries diagnosed?
Measuring the pulse wave velocity (PWV). Using ultrasonic technology to measure arterial stiffness: Ultrasonic apparatus (as used in clinical applications) can be used with relative accuracy to derive distensibility and compliance of the vessel.
What does arterial stiffness mean?
Arterial stiffness describes the rigidity of the arterial wall. In the last decade, there has been increasing interest in the potential role of arterial stiffening in the development of cardiovascular disease in adults.
Can you reverse arterial stiffness?
Is arterial stiffness reversible? Both human and animal studies have suggested that arterial stiffness is reversible.
What is arterial stiffness index test?
Arterial stiffness index (ASI) is a convenient and noninvasive method to measure arterial stiffness by using infrared light (photoplethysmography) to record the volume waveform of the blood in the finger.
What happens if arteries become stiff?
Arterial stiffening, at least in part, reflects gradual fragmentation and loss of elastin fibers and accumulation of stiffer collagen fibers in the arterial wall . Increased arterial stiffness is closely linked to increased risk of hypertension and other diseases, such as chronic kidney disease and stroke .
Why is arterial stiffening bad?
Abstract. Arterial stiffness is a growing epidemic associated with increased risk of cardiovascular events, dementia, and death. Decreased compliance of the central vasculature alters arterial pressure and flow dynamics and impacts cardiac performance and coronary perfusion.
How do you treat arterial stiffness?
Pharmacological treatment such as RAAS antagonists, metformin, and HMG-CoA reductase inhibitors were useful in individuals with hypertension or diabetes. In obese people with OSA, weight reduction, aerobic exercise, and CPAP treatment may improve arterial stiffness as well.
How do you stop arterial stiffness?
Aerobic exercise has been attractive for reducing arterial stiffness since the demonstration of improved systemic arterial compliance and aortic β-stiffness index after as little as 4 weeks of training in healthy, sedentary young adults.
Is arterial stiffness harmful?
Background— Arterial stiffness has been associated with the risk of cardiovascular disease in selected groups of patients. We evaluated whether arterial stiffness is a predictor of coronary heart disease and stroke in a population-based study among apparently healthy subjects.
What dissolves artery plaque?
Cyclodextrin Dissolves Cholesterol Crystals So They Can Be Excreted by Body; Reduces Arterial Wall Inflammation | Journal of Invasive Cardiology.
How does arterial stiffness affect blood pressure?
Increased resistance in small arteries elevates mean BP, and then increases arterial stiffness in the large elastic arteries which, concomitantly with more pressure wave reflections, increases central SBP and 24-hour ambulatory brachial BP variability, ultimately leading to target organ damage.
What causes aortic stiffness?
Aortic stiffness occurs when the elastic fibers within the arterial wall (elastin) begin to fray due to mechanical stress. This is seen with increasing cardiovascular risk factors and aging.
What if the pulse pressure is high?
If your pulse pressure is greater than 60 it’s considered a risk factor for cardiovascular disease, especially for older adults. Stiffness of the body’s largest artery, the aorta, is the leading cause of increased pulse pressure in older adults.