Hereditary aplastic anemia is passed down through the genes from parent to child. It is usually diagnosed in childhood and is much less common than acquired aplastic anemia. People who develop hereditary aplastic anemia usually have other genetic or developmental abnormalities that cause the aplastic anemia.
Are you born with aplastic anemia?
Damage to the bone marrow’s stem cells causes aplastic anemia. When stem cells are damaged, they don’t grow into healthy blood cells. The cause of the damage can be acquired or inherited. “Acquired” means you aren’t born with the condition, but you develop it.
How is aplastic anemia contracted?
The most common cause of aplastic anemia is from your immune system attacking the stem cells in your bone marrow. Other factors that can injure bone marrow and affect blood cell production include: Radiation and chemotherapy treatments.
What is the life expectancy of someone with aplastic anemia?
What are the survival rates for aplastic anemia? Aplastic anemia is a life-threatening condition with very high death rates (about 70% within 1 year) if untreated. The overall five-year survival rate is about 80% for patients under age 20.
Can stress cause aplastic anemia?
For the majority of aplastic anemia patients, doctors cannot find a cause. Stress, overwork and food have no bearing on it.
Can you recover from aplastic anemia?
While drug therapy is not a cure for aplastic anemia, it may partially restore blood cell production. However, up to 50 percent of patients relapse or develop other blood-forming malignancies or disorders. The medications also may be given before a stem cell transplant.
Who is at risk for aplastic anemia?
People of all ages can develop aplastic anemia. However, it’s most common in adolescents, young adults, and the elderly. Men and women are equally likely to have it. The disorder is two to three times more common in Asian countries.
Can aplastic anemia turn into leukemia?
Individuals affected with acquired aplastic anemia are also at risk that it will evolve into another similar disorder known as myelodysplasia. In a minority of cases, acquired aplastic anemia may eventually develop leukemia.
What is the best treatment for aplastic anemia?
A stem cell transplant to rebuild the bone marrow with stem cells from a donor might be the only successful treatment option for people with severe aplastic anemia.
What are the complications of aplastic anemia?
- Severe infections or bleeding.
- Complications of bone marrow transplant.
- Reactions to medicines.
- Hemochromatosis (buildup of too much iron in the body tissues from many red cell transfusions)
What is considered severe aplastic anemia?
Severe aplastic anemia (SAA) is a disease in which the bone marrow does not make enough blood cells for the body.
How I treat aplastic anemia in elderly?
Immunosuppressive regimens – with anti-thymocyte globulin (ATG) associated with cyclosporine-A (CsA), or CsA alone – have been used to treat AA in the elderly, but have been little studied in this population. ATG-CsA regimen is recommended as first line in patients over the age of 60 with severe or very severe AA.
Does a bone marrow transplant cure aplastic anemia?
In contrast, marrow transplantation is associated with high cure rates of aplastic anemia and a relatively low risk for graft-versus-host disease, with many patients now living for decades without the risk for disease recurrence or the development of clonal disorders.
What is the difference between anemia and aplastic anemia?
Many cases of anemia stem from an iron deficiency. These types of anemia are easily treatable. However, aplastic anemia starts with a bone marrow problem and it is not caused by iron deficiency.
What are the 7 types of anemia?
The seven types of anaemia
- Iron deficiency anaemia.
- Aplastic anaemia.
- Haemolytic anaemia.
- Sickle cell anaemia.
- Pernicious anaemia.
- Fanconi anaemia.
Can aplastic anemia cause depression?
With the major challenge of a chronic or even life-threatening disease, patients can easily become depressed and/or anxious about their new health circumstances. The key is to be able to recognize the symptoms and take appropriate action.